Heparin therapy during extracorporeal circulation
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چکیده
منابع مشابه
Heparin therapy during extracorporeal circulation: deriving an optimal activated clotting time during cardiopulmonary bypass for isolated coronary artery bypass grafting.
Bull's seminal work on heparin therapy during cardiopulmonary bypass (CPB) was carried out over 30 years ago and has not been updated in the modern era. No correlation with postoperative blood loss was performed. The optimal activated clotting time (ACT) with regard to blood loss has not been established for patients undergoing CPB. A minimum ACT of 400 is based on the lack of visible formation...
متن کاملThe European working group on heparin coated extracorporeal circulation circuits
Objectives: To evaluate whether the application of heparin treated circuits for elective coronary artery surgery improves postoperative recovery, a European multicenter randomised clinical trial was carried out. Methods: In 11 European heart centers, 805 low-risk patients underwent cardiopulmonary bypass (CPB) with either an untreated circuit (n=407) or an identical but heparin treated circuit ...
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Introduction: Tracheal chondrosarcoma (TCS) is a rare malignancy, with only 19 cases described in the literature to date. Case presentation: Herein, we presented the third-largest TCS with such an airway compromise that neither orotracheal intubation nor jet ventilation or even tracheostomy was possible. So, extracorporeal circulation was needed to excise the tumor in a one-stage procedure. Th...
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Cardiopulmonary bypass, especially when prolonged, may result in hemostatic failure and pulmonary dysfunction, which has been attributed to changes in platelets and leukocytes, respectively. It has been well documented that contact of blood with synthetic surfaces causes platelet activation. In this report, we explore mechanisms of the activation of neutrophils during simulated in vitro extraco...
متن کاملStudies on cardiac lymph during extracorporeal circulation.
Cardiac lymph in dogs was used to study the metabolism and state of the myocardium during extracorporeal circulation and various additional procedures. Changes in the flow characteristics, cdor and pH of lymph were noted, and corresponding samples of cardiac lymph and coronary sinus blood were analyzed for lactate concenlmtion. Ventricular fibrillation led to higher lactate levek when compared ...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1975
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)41500-6